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目的探讨窄波紫外线联合内外应用阿昔洛韦治疗带状疱疹的可行性。方法 129例带状疱疹患者,随机分为阿昔洛韦组(A组,n=63)和联合组(B组,n=66)两组。A组仅采用口服阿昔洛韦片方案进行治疗,B组患者在上述治疗基础上辅以外涂阿昔洛韦软膏联合窄波紫外线方案。记录两组患者疗效及各项症状消退时间,对比其治疗可行性。结果 1 B组患者总有效率为97.0%,明显优于A组患者的76.2%,组间对比差异有统计学意义(P<0.05);2 A组患者神经痛、水疱及结痂时间均长于B组患者,组间对比差异具有统计学意义(P<0.05)。结论采用窄波紫外线联合内外应用阿昔洛韦疗法治疗带状疱疹,疗效显著,可有效缩短恢复期,具有临床推广价值。
Objective To explore the feasibility of using narrow-band UV combined with acyclovir in the treatment of shingles. Methods A total of 129 patients with shingles were randomly divided into two groups: acyclovir (group A, n = 63) and combination group (group B, n = 66). Group A was treated with oral acyclovir only. Patients in group B were supplemented with topical acyclovir ointment and narrow-band ultraviolet (UVA) based on the above treatment. Record the efficacy of two groups of patients and the symptoms of each subsided time, compared to its feasibility of treatment. Results The total effective rate of group B was 97.0%, which was significantly better than that of group A (76.2%). The difference between the two groups was statistically significant (P <0.05). The time of neuralgia, blister and scab in group A was longer than that of group A The difference between the two groups was statistically significant (P <0.05). Conclusion The combination of narrow-band UV and acyclovir in the treatment of shingles with internal and external curative effect is significant, which can effectively shorten the recovery period and has clinical popularization value.