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应用吡喹酮治疗脑囊虫病可出现不同程度的急性颅内压增高,现将我院所见三例报告如下: 例1为女性,30岁。因头痛、呕吐3个月入院。补体结合试验检查为强阳性。前胸及双上肢有十余处皮下结节,活检示为囊虫结节。头颅CT扫描可见两侧大脑半球有20余处散在圆形囊状低密度区,直经约0.5～1.5cm,双侧脑室轻度受压。入院时脑压为190mmH_2O,随后口服吡喹酮每天20mg/kg,服药第2d,头痛加重,呕吐剧烈并伴有嗜睡,脑压达600mmH_2O.经脱水及激素治疗后症状缓解,脑压240mmH_2O,继续服药至6d结束。服药后12d,再次出现剧烈头痛伴呕吐,体温40℃,脑压高达500
The application of praziquantel treatment of cerebral cysticercosis can occur in varying degrees of increased acute intracranial pressure, the hospital now see three cases are as follows: Example 1 female, 30 years old. Due to a headache, vomiting 3 months admitted to hospital. Complement binding test is strongly positive. Forelimb and upper extremity more than ten subcutaneous nodules, biopsy showed cysticercosis nodules. Skull CT scan shows that there are more than 20 hemispheres scattered in the circular cystic low density area, straight through about 0.5 ~ 1.5cm, bilateral ventricular mild compression. On admission, the brain pressure was 190 mmH 2 O, followed by oral praziquantel 20 mg / kg daily for 2 days. The headache was aggravated with severe headache and drowsiness, and the brain pressure was 600 mmH 2 O. The symptoms were relieved after dehydration and hormonal treatment. The intracranial pressure was 240 mmH 2 O, End. After taking medicine 12d, again with severe headache with vomiting, body temperature 40 ℃, intracranial pressure up to 500