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目的探讨米非司酮配伍米索前列醇在死胎引产中的作用。方法对51例妊娠20~42周的死胎孕妇引产分别在1~2日服用米非司酮,总量150~200mg,并于用药前后观察宫颈长度及宫颈评分的变化,第3日晨口服米索前列醇600μg观察引产效果。结果服用米非司酮后宫颈缩短1~3cm(P<005),Bishop评分提高4~5分,宫颈成熟有效率达10000%,引产成功率达9804%。结论应用米非司酮配伍米索前列醇进行死胎引产,显示出成功率高,副作用少的临床价值
Objective To investigate the effect of mifepristone combined with misoprostol in induced labor of stillbirth. Methods Fifty-one pregnant women with stillbirth from 20 to 42 weeks of gestation were treated with mifepristone on the 1st and 2nd day respectively for a total of 150 to 200 mg. Changes of cervical length and cervical score were observed before and after treatment. Supramoetine 600μg observed induction of labor. Results After taking mifepristone, the cervix was shortened by 1 ~ 3 cm (P <005). The Bishop score increased by 4 ~ 5 points. The effective rate of cervical ripening was 10000%. The success rate of induction of labor was 9804%. Conclusion Mifepristone combined with misoprostol for induced abortion of the stillbirth shows the clinical value of high success rate and few side effects