论文部分内容阅读
目的:探索抗病毒药物在治疗小儿手足口病的效果。方法:在肇庆市第一人民医院2013年3月至2016年3月间收治的手足口病患儿中随机选出300例,将其随机分入到观察组和对照组中,两组患者均给予常规治疗,而观察组患者则加用抗病毒药物利巴韦林治疗,对比分析两组患者的治疗总有效率、不良反应发生率、临床症状缓解时间等指标。结果:观察组患儿的总有效率96.67%明显高于对照组患儿的85.33%,差异具有统计学意义(P<0.05);观察组患儿不良反应发生率5.33%略低于对照组的7.33%,差异无统计学意义(P>0.05);观察组患儿在退热时间、疱疹消退时间、口腔溃疡愈合时间上明显短于对照组,差异具有统计学意义(P<0.05)。结论:在小儿手足口病治疗中采用抗病毒药物利巴韦林治疗效果确切,有助于促进患儿的早日康复,且安全性高。
Objective: To explore the effect of antiviral drugs in the treatment of hand, foot and mouth disease in children. Methods: 300 cases of hand-foot-mouth disease were randomly selected from the First People’s Hospital of Zhaoqing from March 2013 to March 2016, and randomly divided into observation group and control group. Both groups The patients in the observation group were treated with ribavirin antiviral therapy. The total effective rate, the incidence of adverse reactions and the clinical symptom relief time were compared between the two groups. Results: The total effective rate in observation group was 96.67%, which was significantly higher than that in control group (85.33%), the difference was statistically significant (P <0.05). The incidence of adverse reactions in observation group was slightly lower than that in control group 7.33% respectively. There was no significant difference between the two groups (P> 0.05). The observation group was significantly shorter than the control group in the time of fever withdrawal, herpes remission and the healing of oral ulcer. The difference was statistically significant (P <0.05). Conclusion: Ribavirin, an antiviral drug, is effective in the treatment of childhood hand-foot-mouth disease, which will help to promote the early recovery of children with high safety.