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本文观察了淋巴因子激活的杀伤细胞(LAK)在体外对人肝癌细胞株(H_(7402))的杀伤活性及透射电镜下LAK细胞对H_(7402)的杀伤作用.实验证实:LAK细胞对人肝癌细胞H_(7402)有较强的杀伤活性;而对正常人外周血淋巴细胞无杀伤作用;透射电镜下:LAK细胞与H_(7402)细胞共同孵育30分钟,可见二种细胞各自伸出突起,互相接触.共同培养4小时,可见,H_(7402)细胞呈“凋零”坏死.
The killing activity of lymphokine-activated killer cells (LAK) on human hepatoma cell lines (H 7402) and the killing effect of LAK cells on H 7402 under transmission electron microscopy were observed. Hepatoma cells H_(7402) had a strong killing activity; but no killing effect on normal human peripheral blood lymphocytes; under transmission electron microscope: LAK cells were incubated with H_(7402) cells for 30 minutes, and it was seen that both cells protruded , In contact with each other. Co-cultured for 4 hours, visible, H_ (7402) cells were “fallen” necrosis.