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用99mTc-DTPA肾动态显像对26例正常人及23例肾小球肾炎患者进行了观察。按肾功能影像从浓到淡将肾小球肾炎分成肾炎1、2、3组。结果表明:3组均有全肾平均通过时间延长、20min/高峰升高及肾脏指数下降。随着肾影的变淡,GFR呈明显下降趋势(P<0.01),本底计数/高峰肾脏计数呈明显增高趋势(P<0.01)。肾炎2组已有较明显的肾功能异常,应进行积极有效的非透析治疗。肾炎3组的肾功能严重受损,应进行透析治疗。结论:肾动态显像在客观评价肾小球肾炎患者的肾功能方面有重要价值,可用于对慢性肾衰进行分期并帮助确定治疗方案。
Twenty-six normal subjects and 23 patients with glomerulonephritis were observed with 99mTc-DTPA renal dynamic imaging. According to renal function images from thick to light glomerulonephritis divided into nephritis 1,2,3 group. The results showed that: the average of the three groups were extended through the whole kidney, 20min / peak and renal index decreased. The GFR showed a significant decrease (P <0.01), while the background count / peak renal count increased significantly (P <0.01). Nephritis group 2 has more obvious renal dysfunction, should be active and effective non-dialysis treatment. Nephritis 3 groups of severely impaired renal function, dialysis should be carried out. Conclusion: Renal dynamic imaging is of great value in the objective evaluation of renal function in patients with glomerulonephritis. It can be used to stage chronic renal failure and help to determine the treatment plan.