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[目的]分析胃癌、大肠癌的根治过程与血行转移的相关性。[方法]试验组(91例)首先结扎肿瘤区域流向门静脉血流途径,并再从门静脉血取样,而对照组(181例)则直接取样。两组均以抗上皮细胞膜单克隆抗体为探针,ABC免疫组化法检测血中癌细胞。[结果]试验组阳性率19.8%(18/91),3年、5年的生存率分别为72%和58%;对照组阳性率为66.8%(121/181),3年、5年的生存率分别为52%和34%。两组间差异有显著性(P<0.05)。[结论]手术是导致癌细胞转移的危险性因素,去血管的肿瘤清扫术,可能会有效防止癌细胞转移。
[Objective] To analyze the correlation between the radical process of gastric cancer and colorectal cancer and blood metastasis. [Method] The experimental group (91 cases) first ligation of the tumor area to the portal vein flow pathways, and then sampling from the portal vein, while the control group (181 cases) were directly sampled. Anti-epithelial cell membrane monoclonal antibody was used as a probe in both groups, and ABC immunohistochemistry was used to detect blood cancer cells. [Results] The positive rate of test group was 19.8% (18/91), and the survival rates of three and five years were 72% and 58% respectively. The positive rate of control group was 66.8% (121/181), three years and five years Survival rates were 52% and 34% respectively. The difference between the two groups was significant (P <0.05). [Conclusion] Surgery is a risk factor leading to metastasis of cancer cells. Tumor removal to blood vessels may effectively prevent the metastasis of cancer cells.