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本文作者鉴于从细胞形态学特点来鉴别白血病类型存在一定的困难,故对22例未治急淋作了糖原的细胞化学检查,用以诊断细胞类型以及确定预后和细胞化学之间的关系。用糖原半定量计数法,原始细胞积分0～400不等。高于60％阳性细胞者为强阳性组;低于55％阳性细胞者为弱阳性组。并同时做了苏丹黑B及过氧化酶等细胞化学检查。采用治疗方法为:长春新硷/周和强的松/天共4～6周,缓解后给中枢神经系统白血病预防性治疗,维持治疗用6巯基嘌呤/天,氨甲喋呤及环磷酰胺/周。
In view of the difficulty of identifying leukemia types from cell morphological traits, the authors performed cytochemical tests on untreated glycogen to diagnose cell types and determine the relationship between prognosis and cytochemistry. Semi-quantitative counting with glycogen method, the original cell score 0 ~ 400 range. More than 60% positive cells were strongly positive group; less than 55% positive cells were weak positive group. And at the same time to do Sudan black B and peroxidase and other cytochemical tests. The treatment method is: vincristine / week and strong pine / day a total of 4 to 6 weeks, after remission for central nervous system leukemia prophylaxis treatment, maintenance therapy with 6-mercaptopurine / day, methotrexate and cyclophosphamide / week.