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目的:了解山东省新型冠状病毒肺炎(Coronavirus Disease 2019, COVID-19)密切接触者感染率并探讨影响感染的危险因素。方法:收集山东省新型冠状病毒(2019 novel coronavirus, 2019-nCoV)感染者所有密切接触者相关信息，进行描述性流行病学分析，通过n Logistic回归分析危险因素。n 结果:截至2020年3月6日，山东省累计报告密切接触者15 702人，其中321例感染2019-nCoV，感染率为2.04%。各因素中，感染率最高的前5位分别是，近亲属感染率最高，为13.39%，经常接触感染率为9.58%，同室工作/居住/学习感染率为7.54%，接触病例人数为2例及以上感染率为4.58%，>60岁以上组感染率为3.10%。单因素分析显示，接触病例的人数为2例及以上组、>60岁年龄组、与接触对象的关系为近亲属组、经常接触组、同室工作/居住/学习组是密切接触者感染的危险因素。多因素分析显示，接触2例及以上病例(n OR＝2.510, 95%n CI: 1.843~3.417)、30~60岁年龄组(n OR＝1.513, 95%n CI: 1.141~2.007)、经常接触组(n OR＝20.025, 95%n CI: 14.625~27.419)、同室工作/居住/学习(n OR＝2.406，95%n CI：1.385~4.182)和医疗机构内接触(n OR＝2.366，95%n CI: 1.149~4.871)是密切接触者感染的危险因素。n 结论:追踪管理密切接触者，是控制COVID-19疫情的重要措施；减少聚集、保持适当的社交距离、采取有效防护等是控制2019-nCoV感染的有效手段。“,”Objective:To understand the infection rate of Coronavirus Disease 2019 (COVID-19) in close contacts in Shandong province and explore the risk factors of infection.Methods:All data from close contacts of 2019 novel coronavirus (2019-nCoV) infected persons in Shandong province were collected for descriptive epidemiological analysis, and risk factors were analyzed by logistic regression.Results:Up to March 6, 2020, a total of 15 702 close contacts had been reported in Shandong province, of whom 321 cases were infected with 2019-nCoV, with an infection rate of 2.04%. Among all the factors, the top five with the highest infection rate were close relatives (13.39%), frequent contact (9.58%), working/living/studying in the same room (7.54%), two or more contact cases (4.58%), and over 60 years old (3.10%). Single-factor analysis showed that exposure to two or more cases, over 60 years old, close relatives with cases, frequent contact and working/living/studying in the same room were the risk factors for infection in close contacts. Multivariate analysis showed that exposure to two or more cases (n OR=2.510, 95% n CI: 1.843-3.417), 30~60 year old group (n OR=1.513, 95% n CI: 1.141-2.007), frequent exposure group (n OR=20.025, 95% n CI: 14.625-27.419), working/living/learning in the same room (n OR=2.406, 95% n CI: 1.385-4.182) and medical institution exposure (n OR=2.366, 95% n CI: 1.149-4.871) were risk factors of infection in close contacts.n Conclusions:Tracking and managing close contacts was an important measure to control the COVID-19 epidemic situation, and reducing crowd concentration, keeping a proper social distance and taking effective protection were effective measures to control 2019-nCoV infection.