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目的 探讨白细胞介素 - 10 (IL - 10 )在人脑胶质瘤发生发展中的作用。方法 采用逆转录聚合酶链反应 (RT- PCR)方法检测 IL - 10 m RNA在人脑胶质瘤细胞中的表达。结果表明 ,17例新鲜人脑胶质瘤标本中有 15例表达 IL - 10 m RNA,提示免疫抑制因子 IL - 10在脑胶质瘤中的表达可能是导致脑胶质瘤患者免疫功能低下的原因之一。
Objective To investigate the role of interleukin - 10 (IL - 10) in the development of human glioma. Methods The expression of IL - 10 mRNA in human glioma cells was detected by reverse transcriptase - polymerase chain reaction (RT - PCR). The results showed that IL - 10 mRNA was expressed in 15 of 17 fresh human gliomas, suggesting that the expression of IL - 10 in glioma may be the result of immunocompromised patients with glioma. one of the reasons.