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目的探讨74例慢性阻塞性肺疾病(COPD)患者在急性加重期使用抗菌药物治疗的情况。方法回顾分析广东省佛山市三水区人民医院2009年5月至2013年12月收诊的74例Ⅱ、Ⅲ级慢性阻塞性肺疾病急性加重期(AECOPD)患者,统计和分析使用抗菌药物治疗的情况。结果 74例AECOPD患者中,年发病率2次以上有(70±15)例次;有73例(98.6%)使用了抗菌药物,治疗总有效率为93.2(69/74);共使用20种抗菌药物,有9种DUI>1,占45.0%,其他11种DUI≤1,占55.0%。结论 AECOPD患者使用抗菌药物进行治疗的方案基本合理,但部分仍需继续完善,有必要对其使用抗菌药物情况进行分析,提高抗菌药物的合理使用率,降低治疗费用。
Objective To investigate the use of antimicrobial agents in 74 patients with chronic obstructive pulmonary disease (COPD) during acute exacerbations. Methods A retrospective analysis of 74 patients with grade Ⅱ and Ⅲ acute exacerbation of chronic obstructive pulmonary disease (AECOPD) admitted to Sanshui District People ’s Hospital of Foshan City, Guangdong Province from May 2009 to December 2013 was conducted. Statistics and analysis of the use of antimicrobial agents Case. Results Among the 74 patients with AECOPD, the annual morbidity was more than 2 times (70 ± 15), 73 (98.6%) were antibacterials, and the total effective rate was 93.2 (69/74). A total of 20 Antimicrobial drugs, 9 DUI> 1, accounting for 45.0%, the other 11 DUI ≤ 1, accounting for 55.0%. Conclusion AECOPD patients with antimicrobial drugs for treatment of the program is reasonable, but some still need to continue to improve, it is necessary to analyze the use of antimicrobial agents to improve the rational use of antimicrobial agents and reduce treatment costs.