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来越多的证据表明，１型糖尿病是Ｔ淋巴细胞介导的自身免疫性疾病，其主要的病理学改变是胰岛单核细胞浸润，包括ＣＤ８＋和ＣＤ４＋Ｔ淋巴细胞、Ｂ淋巴细胞、自然杀伤细胞和巨噬细胞。非肥胖糖尿病（Ｎｏｎｏｂｅｓｅｄｉａｂｅｔｉｃ，ＮＯＤ）小鼠其胰岛炎和糖尿病的发...
Increasing evidence suggests that type 1 diabetes is a T-lymphocyte-mediated autoimmune disease whose major pathological changes are islet monocyte infiltration including CD8 + and CD4 + T lymphocytes, B lymphocytes, natural killer cells and Macrophages. Nonobese diabetic (NOD) mice with insulitis and diabetes ...