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目的：本研究探讨不能手术切除的中晚期肝癌行介入治疗后的再治疗方法。材料和方法：９２例中晚期肝癌患者行肝动脉栓塞（ＴＡＥ）治疗后其中５０例（甲组）获二期手术切除，另４２例（乙组）重复行ＴＡＥ治疗。对比观察两组的临床疗效。结果：甲组１、２年累计生存率分别为７１％和５０％，乙组１、２年累计生存率为７３％和４３％，二组间无显著差异。甲组ＯｋｕｄａＩ期患者的生存率优于乙组，而ＯｋｕｄａⅡ期患者的生存率乙组优于甲组。结论：中晚期肝癌行ＴＡＥ治疗后二期手术切除的必要性尚有待讨论，二期切除不能改善ＯｋｕｄａⅡ期患者的生存情况。
OBJECTIVES: This study investigated the retreatment of unresectable advanced hepatocellular carcinoma after interventional therapy. Materials and Methods: Of the 92 patients with advanced liver cancer undergoing hepatic artery embolization (TAE), 50 (Group A) were treated with a second-stage resection and the other 42 (Group B) were treated with TAE. The clinical efficacy of the two groups was compared. Results: The cumulative survival rate of group 1 and 2 was 71% and 50% respectively. The cumulative survival rate of group 1 and 2 was 73% and 43%. There was no significant difference between the two groups. The survival rate of patients with Stage I Okuda was better than that of Group B, while the survival rate of Stage II patients with Okuda was better than Group B. Conclusion: The necessity of secondary surgical resection after TAE treatment in advanced hepatocellular carcinoma remains to be discussed. Secondary resection can not improve the survival of patients with stage II Okuda.