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目的:评价短程放疗方案对转移癌脊髓压迫症的近期疗效及毒副反应。方法:1991年1月至1999年10月,对43例因转移癌引起的脊髓压迫症行短程放疗400cGy/次×5次/周,总量 20Gy,放疗同时辅以激素加脱水剂以预防放射所致的急性水肿。观察背痛、运动功能及括约肌功能变化情况。结果:43例转移癌脊髓压迫症患者背痛缓解、运动功能改善和括约肌功能恢复有效率分别为 81.4%、72.1%和50.0%。无明显毒副反应。结论:短程放疗治疗转移癌脊髓压迫症,毒副反应轻,是一种合适有效的治疗方案。
OBJECTIVE: To evaluate the short-term efficacy and toxicity of short-range radiotherapy in metastatic cervical spinal cord compression. Methods: From January 1991 to October 1999, 43 cases of spinal cord compression caused by metastatic cancer were treated with brachytherapy 400cGy / time × 5 times / week, with a total amount of 20Gy. Radiotherapy combined with hormone plus dehydrating agent Prevention of acute edema caused by radiation. Observe the changes of back pain, motor function and sphincter function. Results: In 43 patients with spinal cord compression disease, the pain relief, motor function improvement and sphincter recovery were 81.4%, 72.1% and 50.0% respectively. No obvious side effects. Conclusion: Short-range radiotherapy is a suitable and effective treatment for the treatment of spinal cord compression syndrome of metastatic carcinoma with light toxicity.