为探讨在临床应用中影响西地那非治疗勃起功能障碍(ED)效果的因素。Hatzichristou D等筛选了100名对西地那非无反应的患者(平均年龄59±14．4岁,平均ED病史5．5±6．4年)进行研究。详细询问所有患者的用药史和性生活史,要求他们填写IIEF问卷和既往西地那非使用情况的问卷。如果患者既往未得到充分的用药指导,那么将教授其如何正确使用西地那非并且要求其在家中至少再服用4片万艾可。之后随访时重新评价药物疗效。结果,IIEF中勃起功能的平均 To explore the clinical application of sildenafil treatment of erectile dysfunction (ED) factors. Hatzichristou D et al. Screened 100 patients who did not respond to sildenafil (mean age 59 ± 14.4 years, mean ED history 5.5 ± 6.4 years). Asked in detail about the medication history and sex life history of all patients and asked them to complete the questionnaire for the IIEF questionnaire and for the past use of sildenafil. If the patient has not been adequately medically instructed in the past, then he will be taught how to use sildenafil properly and ask him to take at least four more in the home. After follow-up re-evaluation of drug efficacy. Results, the average of erectile function in IIEF