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目的:了解我院药品不良反应(ADR)发生的特点及规律。方法:回顾性分析我院2013年收集的306例药品不良反应报告,对患者性别、年龄、给药途径、药物类别、ADR累及系统/器官和临床表现、分类情况、因果关系评价以及报告人员构成比等进行统计分析。结果:306例ADR报告中,51~60岁患者发生ADR例数构成比最高(20.26%);给药途径以静脉滴注引起的ADR例数构成比最高(65.58%);药品类别以抗菌药引起的ADR例数构成比最高(20.78%);ADR累及系统以消化系统为主,占23.91%;医师报告的数量最多,占97.71%。结论:我院应加强对ADR的监测和报告,促进临床合理用药,降低ADR风险,保障患者用药安全。
Objective: To understand the characteristics and laws of adverse drug reaction (ADR) in our hospital. Methods: A retrospective analysis of 306 adverse drug reactions (ADRs) collected in our hospital in 2013 was conducted to evaluate the gender, age, route of administration, drug category, system / organ and clinical manifestations, classification of ADRs, causal relationships and the composition of reporters Than for statistical analysis. Results: Among the 306 ADR cases, the highest proportion of cases with ADR (20.26%) occurred in patients 51 to 60 years old. The composition ratio of ADR cases caused by intravenous drip injection was the highest (65.58%). Antibiotics ADR caused by the highest proportion of cases (20.78%); ADR involving the digestive system dominated system, accounting for 23.91%; physicians reported the largest number, accounting for 97.71%. Conclusion: Our hospital should strengthen the monitoring and reporting of ADR, promote clinical rational use of drugs, reduce the risk of ADR and ensure the safety of patients.