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巨噬细胞是一种位于组织内的白细胞,作为重要的固有免疫细胞,其功能是吞噬死亡的细胞残片和病原体,通过膜上或胞内的模式识别受体(pattern recognition receptors,PRRs)识别病原相关分子模式(pathogen-associated molecular patterns,PAMPs),诱导信号通路的级联放大,从而分泌炎症因了和趋化因子等来抗击病原体,而且还可以激活、辅助T细胞活化。当
Macrophages, a type of leukocyte located within a tissue, function as an essential innate immune cell that phagocytizes dead cell debris and pathogens and recognizes pathogens through pattern recognition receptors (PRRs) on or in the membrane Pathogen-associated molecular patterns (PAMPs) induce cascades of signaling pathways to secrete inflammatory cytokines and chemokines to combat pathogens, but also activate and assist T cell activation. when