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目的探讨COPD病人并发的带状疱疹的临床特征及治疗方案。方法回顾性分析12例COPD病人并发带状疱疹的临床资料。结果COPD病人多为老年患者,身体一般情况差,加上长期反复使用糖皮质激素,机体免疫力低下,容易并发带状疱疹,寻常型所占比例较高。几乎所有患者均伴有严重的神经痛,且神经痛开始时间早于皮疹出现,而消失时间明显滞后皮疹消退,病程长,容易误诊。临床表现寻常型,仅给以阿昔洛韦静滴抗病毒;临床表现特殊型者,予阿昔洛韦联合丙种球蛋白静滴。所有病例均获痊愈,治疗总有效率100%。结论COPD病人易并发带状疱疹,其病情常较重。治疗时不仅给于抗病毒治疗,还应相应给予调整免疫治疗。
Objective To investigate the clinical characteristics and treatment of herpes zoster complicated by COPD. Methods The clinical data of 12 patients with COPD complicated with herpes zoster were analyzed retrospectively. Results Most of COPD patients were elderly patients. Their body condition was poor. Coupled with long-term repeated use of glucocorticoids, the body immunity was low, and herpes zoster was easy to be complicated. The proportion of common type was higher. Almost all patients were accompanied by severe neuralgia, and neuralgia started earlier than the rash, but disappeared significantly delayed disappearance of the rash, longer duration, easy misdiagnosis. The clinical manifestations of anomaly, only given intravenous acyclovir antiviral; special clinical manifestations, to acyclovir intravenous gamma globulin. All cases were cured, the total effective rate of 100%. Conclusions Patients with COPD are prone to shingles and their condition is often severe. Not only for treatment of antiviral therapy, immunotherapy should be adjusted accordingly.