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目的:探讨金钠多与胞磷胆碱的配伍稳定性。方法:将金钠多与胞磷胆碱根据临床常用剂量按比例配伍后观察溶液外观,测定pH值、薄层色谱及测定含量。结果:在25℃条件下6 h内混合液外观、pH值、薄层色谱均无变化,金钠多与胞磷胆碱含量无明显变化。结论:金钠多与胞磷胆碱配伍混合液稳定。
Objective: To investigate the stability of compatibility of sodium and sodium citicoline. Methods: The sodium and sodium citrate and citicoline according to the proportion of commonly used clinical dose of compatibility observed after the appearance of the solution, the determination of pH, TLC and determination of content. Results: There was no change in the appearance of the mixed solution within 6 h at 25 ℃, pH value and TLC. No significant changes were found in the contents of sodium and citicoline. Conclusion: The sodium and sodium and citicoline compatibility mixture was stable.