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目的 分析探讨百草枯中毒的胸部 CT表现特征。方法 回顾性观察分析 18例百草枯中毒病人的胸部CT影像学表现 (其中应用 CT规律观察 12例 ,6例只有一周内胸部 CT影像资料 ,8例次行 HRCT)。结合临床 ,总结肺、纵隔及胸壁 CT的影像学特征。结果 18例中 12例存活 3周以上的患者 ,中毒早期 (2天以内 ) ,其中 6例肺出现通气过度及局限性浅淡毛玻璃密度 ,6例胸部无明显改变。中期 (3～ 14天 ) ,12例均出现胸部 CT影像的明显变化 ,以广泛毛玻璃密度、肺实性变、渗出性病变、肺间质改变为主 (分别占 91.7%、66.7%、91.7%、10 0 % ) ,出现胸腔积液 7例 ,心包积液 4例。中后期 (14天以上 )变化不显著 ,表现以肺渗出、实变、肺纤维化为主。另 6例中毒程度严重者 ,中早期即以渗出性病变及肺实变为主。结论 百草枯中毒的胸部 CT表现具有一定的特征性 ,其影像学变化对病情发展及指导临床治疗具有重要意义
Objective To analyze and discuss the chest CT features of paraquat poisoning. Methods The CT findings of 18 patients with paraquat poisoning were retrospectively analyzed. Among them, 12 cases were observed by CT, 6 cases had CT data of one week only, and 8 cases were performed HRCT. Combined with clinical, summarize the lung, mediastinum and chest wall CT imaging features. Results Twelve of the 12 patients survived more than 3 weeks and were poisoned early (within 2 days). In 6 of them, hyperventilation occurred in the lung and the density of frosted glass was shallow. There was no significant change in 6 cases of the chest. In the medium term (range, 3 to 14 days), there were significant changes in CT findings of the thoracic region in all 12 cases, with extensive gross glass densities, solid lung lesions, exudative lesions and interstitial lung masses (91.7%, 66.7%, 91.7 %, 100%), pleural effusion in 7 cases, 4 cases of pericardial effusion. The late period (more than 14 days) did not change significantly, the performance of pulmonary exudation, consolidation, pulmonary fibrosis based. Another 6 cases of severe poisoning, in the early that exudative lesions and lung consolidation. Conclusion Paraquat poisoning of chest CT has some characteristics of the imaging changes of the disease development and clinical guidance is of great significance