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为进一步阐明着床的分子机制，为生育的控制和不孕症的治疗提供新的实验基础，利用十二烷基硫酸钠－聚丙烯酰胺凝胶电泳（ＳＤＳ－ＰＡＧＥ）及银染法对正常人增殖期（ＰＰ）、分泌期（ＳＰ）、以及尽可能接近于着床期（早早孕期）包括二级绒毛期（ＳＶＰ）和三级绒毛期（ＴＶＰ）的子宫内膜蛋白质进行了研究，结果发现：子宫内膜水溶性蛋白质于增殖期含量最高，增殖期后降低，存在显著性差异（Ｐ＜００５），而十二烷基硫酸钠（ＳＤＳ）溶解蛋白在各个功能时期无显著性差异（Ｐ＞００５）；早早孕期人子宫蜕膜蛋白质有阶段特异性变化，有４５７千道尔顿（ｋＤ）阶段特异性蛋白出现。其确切的功能以及在胚泡着床过程中的作用均待进一步阐明
In order to further clarify the molecular mechanism of implantation, provide a new experimental basis for fertility control and treatment of infertility, using sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) and silver staining method for normal Human proliferative phase (PP), secretory phase (SP), and endometrial proteins as close as possible to implantation (early pregnancy) including secondary villus (SVP) and tertiary villus (TVP) The results showed that the content of water-soluble protein in endometrium was the highest during the proliferative phase and decreased after the proliferative phase (P <005), while SDS-dissolved protein had no significant difference at all functional stages (P> 005). The protein in early stage of human uterine decidual phase had specific changes, and 45.7 kD phase-specific proteins appeared. Its exact function and role in blastocyst implantation are to be further elucidated