目的 探究循证护理(EBN)在乳腺癌改良根治术(BCMRO)围手术期护理中的应用效果，为临床护师选择合理护理方案提供参考?方法 选取2018 年6 月至2019 年5 月在本院接受BCMRO 治疗患者的82 例乳腺癌患者，将其随机编号后利用数表法分为对照组?试验组，各41 例?对照组患者接受常规护理，试验组患者实施EBN，比较两组患者的情绪状态和并发症发生情况，并记录两组的满意度情况?结果 护理前，两组患者的焦虑自评量表(SAS)?抑郁自评量表(SDS)评分比较无差异(P > 0.05);护理后， 两组患“,”Objective To explore the application effect of evidence-based nursing in the perioperative nursing of breast cancer modified radical operation， so as to provide reference for clinical nurse to choose reasonable nursing plan. Methods Taking the period from June 2018 to May 2019 as the research stage， we selected 82 patients who underwent modified radical mastectomy for breast cancer in our hospital during this period. They were randomly numbered and divided into the control group and the test group using a number table， 41 cases in each group. Patients in the control group received routine care， and patients in the experimental group received evidence-based care. The emotional state and complication rates of the two groups were compared， and the satisfaction of the two groups was recorded. Results Before nursing， there was no significant difference between the two groups in Self-rating Anxiety Scale (SAS) and Self- rating Depression Scale (SDS) (P >0.05). After nursing， SAS and SDS scores of the two groups were lower than before (P <0.05)， and the score of the experimental group was lower than that of the control group (P <0.05). The incidence of complications in the experimental group was 2.44%， lower than 14.64% of the control group， the difference was statistically significant (P <0.05). The satisfaction rate of patients in the experimental group was 87.80%， which was higher than 60.98% in the control group， and the difference was statistically significant (P <0.05). Conclusion In the perioperative nursing of breast cancer patients with modified radical mastectomy， the implementation of evidence-based nursing is conducive to the prevention of complications and the improvement of patients\' psychological state， easy for patients to accept and approve.