甾体皂苷,对于扩张冠状动脉、减少动脉粥样硬化和降血脂有很强的作用,但它很难提取,只在实验室中以克量级制造、储备。20世纪30年代以来,美、日、英等国曾投巨资进行甾体皂苷规模化制备的攻关,均以失败告终。1981年,以李伯刚为首的中科院课题组发现:我国特有的蕴藏量最大的穿龙薯蓣的活性成分有多种甾体皂苷,对于治疗冠心病、心绞痛有很好的效果,如能够进入临床,将有希望造福于成千上万的冠心病患者。然而,一个世界性的难题摆在了课题组面前——甾体皂苷只能在实验室以克为单位小剂量提取,提取代价非常昂贵,应用到临床很不现实。1982开始,李伯刚几乎是把甾体皂苷工业化生产的课题研究当做了一切,每天都要工作十多 Steroidal saponins, for the expansion of the coronary artery, reduce atherosclerosis and lipid-lowering have a strong role, but it is difficult to extract, only in the laboratory to create, reserve on the order of grams. Since the 1930s, the United States, Japan, Britain and other countries have invested heavily in the preparation of steroidal saponins large-scale preparation, failed. In 1981, the Chinese Academy of Sciences led by Li Bogang Task Force found that: the largest of our unique reserves of Dioscorea nipponica active ingredient has a variety of steroidal saponins, for the treatment of coronary heart disease, angina have a good effect, such as being able to enter the clinic, will Hope for the benefit of thousands of coronary heart disease patients. However, a worldwide problem lies in front of the group - steroid saponins can only be extracted in small doses in the laboratory in grams, the extraction is very expensive, and it is impractical to apply it to the clinic. Beginning in 1982, Li Borgang almost all the subject of industrial production of steroidal saponins as everything, work more than 10 every day