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为了观察曾接受治疗的乳腺癌妇女对黄体期孕酮的某些生理反应是否正常,评价孕酮抵抗在乳腺癌发生中的作用,选取25例平均年龄39岁的正常妇女与30例平均年龄40岁的曾患乳腺癌,并在2～4年前接受外科治疗的妇女进行研究,以孕酮的生热效应作为衡量激素活性的指标。在一个自然月经周期中,每天测量口腔基础温度,用置入胸罩内半导体电阻测温仪测量乳腺表面温度和放免法测定唾液中孕酮的浓度,根据唾液中孕酮峰浓度日(周期
In order to observe whether some of the physiological responses to progesterone during luteinization in women with breast cancer who received treatment were normal, and to evaluate the role of progesterone resistance in the development of breast cancer, 25 women with a mean age of 39 years and 30 women with an average age of 40 were selected. A woman who had had breast cancer and had undergone surgical treatment 2-4 years ago was studied and used the progesterone’s thermogenic effect as an indicator of hormone activity. In a natural menstrual cycle, the oral cavity temperature is measured daily, the surface temperature of the mammary gland is measured with a semiconductor resistance thermometer placed inside the bra, and the concentration of progesterone in the saliva is measured by radioimmunoassay, according to the concentration of progesterone peak in the saliva.