肝脏血流减少或阻断见于很多临床情况,本文主要介绍防治肝脏缺血的近代见解。肝缺血时细胞损伤的机制肝缺血时以及再灌注后均可发生细胞损害。有人认为缺氧是最重要的因素,但缺血时,氧和底物供应不足以及代谢物的积累均可引起细胞损害,细胞能量值迅速减少,各种细胞和亚细胞功能发生紊乱,诸如线粒体功能不良、细胞膜功能损害和蛋白合成减少等。近年来注意 Reduced or blocked hepatic blood flow seen in many clinical situations, this article describes the modern ideas to prevent and treat liver ischemia. Mechanisms of cellular damage during hepatic ischemia Cell damage can occur during liver ischemia and after reperfusion. Some people think hypoxia is the most important factor, but ischemia, lack of oxygen and substrate supply and accumulation of metabolites can cause cell damage, the rapid decline in cell energy value, a variety of cellular and subcellular dysfunction, such as mitochondria Dysfunction, impaired cell membrane function and decreased protein synthesis. In recent years attention