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目的:探讨不同孕龄胎膜早破终止妊娠的最佳时机,以改善围生儿预后。方法:回顾性分析383例胎膜早破患者的临床资料,并对其进行合理分组讨论和统计学处理。结果:①孕28-32周PROM的新生儿应用呼吸机、新生儿呼吸窘迫综合征、新生儿感染、颅内出血、死亡的发生率最高(P<0.05)。②总体来看,随着期待治疗时间的延长,感染的发生率均增高,对于32-34周的PROM可以适当给予期待治疗延长孕周,新生儿呼吸窘迫综合征的发生率会显著降低。③>34周PROM期待治疗会增加感染的发生率。结论:临床医生应该根据实际情况在全面评估患者和充分医患沟通后选择合适的终止妊娠时机。
Objective: To explore the best timing of termination of pregnancy in different gestational age premature rupture of membranes in order to improve the prognosis of perinatal children. Methods: A retrospective analysis of 383 cases of premature rupture of membranes in patients with clinical data, and its reasonable group discussion and statistical analysis. Results: The neonatal respiratory distress syndrome, neonatal infection, intracranial hemorrhage and death were the highest in neonates with PROM at 28-32 weeks’ gestation (P <0.05). ② Overall, with the prolonged treatment, the incidence of infection was increased. For PROMs 32-34 weeks, expectant treatment was prolonged and the incidence of neonatal respiratory distress syndrome was significantly reduced. ③> 34 weeks PROM expectant treatment will increase the incidence of infection. Conclusion: Clinicians should select the appropriate timing of termination of pregnancy after a thorough assessment of patients and full communication between patients and patients based on the actual situation.