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探讨血小板/白细胞比值在预测肾综合征出血热患者出血中的价值。方法比较56例不同出血程度的肾综合征出血热患者血小板计数与血小板/白细胞比值。结果Ⅰ°、Ⅱ°与Ⅲ°出血间血小板计数分别为(73.46±25.05)×109/L、(52.23±23.09)×109/L和(39.08±18.24)×109/L,方差分析表明Ⅰ°与Ⅱ°出血间及Ⅰ°与Ⅲ°出血间差异有显著性(P<0.01),Ⅱ°与Ⅲ°出血间差异无显著性;Ⅰ°、Ⅱ°与Ⅲ°出血间血小板/白细胞比值分别为11.91±6.77、5.39±3.20和2.55±0.92,方差分析表明各个出血程度间差异均有显著性(P<0.01)。人为设定一血小板/白细胞比值(7.14)并观察不同出血程度组中低于该比值的检出率,发现在Ⅱ°与Ⅲ°出血组检出率分别为70.59%和100%,而血小板低于50×109/L的检出率却分别为58.33%和61.54%,统计学处理差异有显著性(P<0.01)。结论在不同出血程度间血小板/白细胞比值的差异具有显著性。以血小板/白细胞比值来预测大出血的发生具有早期、准确的价值。
To investigate the value of platelet / leukocyte ratio in predicting bleeding in patients with hemorrhagic fever with renal syndrome. Methods Fifty-six patients with hemorrhagic fever with renal syndrome with different degree of hemorrhage were compared for platelet count and platelet / leukocyte ratio. Results The platelet counts of hemorrhage between Ⅰ °, Ⅱ ° and Ⅲ ° were (73.46 ± 25.05) × 109 / L, (52.23 ± 23.09) × 109 / L and (39.08 ± 18. 24) × 109 / L. Analysis of variance showed that there was significant difference between Ⅰ ° and Ⅱ ° hemorrhage and between Ⅰ ° and Ⅲ ° hemorrhage (P <0.01), but no significant difference between Ⅱ ° and Ⅲ ° hemorrhage °, Ⅱ ° and Ⅲ ° hemorrhage platelet / leukocyte ratio were 11.91 ± 6.77,5.39 ± 3.20 and 2.55 ± 0.92, analysis of variance showed significant differences between the various bleeding (P <0.01). Artificially set a platelet / leukocyte ratio (7.14) and observed in different hemorrhage degree group was lower than the ratio of the detection rate found in Ⅱ ° and Ⅲ ° hemorrhage detection rates were 70.59% and 100% , While the detection rate of platelets less than 50 × 109 / L were 58.33% and 61.54%, respectively. There was significant difference between the two groups in statistics (P <0.01). Conclusions The difference of platelet / leukocyte ratio between different hemorrhage levels is significant. To platelet / leukocyte ratio to predict the occurrence of major bleeding with early, accurate value.