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对31例新生儿硬肿症进行了血清超氧化物歧化酶（SOD）、丙二醛（MDA）和维生素E（VE）的测定并与21例正常新生儿对照。结果发现，硬肿患儿SOD活性明显低于对照组（P＜0．001），并且下降程度与硬肿程度相关；MDA含量明显高于对照组（P＜0．05），但与硬肿程度无明显关系；VE含量低于对照组，但无统计学差别。硬肝患儿经抗氧化剂和东莨菪碱治疗后硬肿消失的时间分别是5．22±1．40天和4．86±1．72天，两种方案的治疗效果无明显差别（p＞0．05）。
Serum SOD, MDA and vitamin E (VE) were measured in 31 neonates with scleredema and were compared with 21 normal neonates. The results showed that the activity of SOD in children with edema was significantly lower than that in the control group (P <0.001), and the degree of descent was related to the degree of edema. The content of MDA was significantly higher than that of the control group (P <0.05) No significant relationship between the degree of VE content lower than the control group, but no statistical difference. The time of disappearance of sclerosis after treatment with antioxidants and scopolamine in children with cirrhosis was 5.22 ± 1.40 days and 4.86 ± 1.72 days, respectively. There was no significant difference between the two regimens (p> 0.05). 05).