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方法:利用姐妹染色单体互换频率、B型超声、宫高及腹围三种指标综合判断产前诊断胎儿生长迟缓。目的:以提高产前诊断率及建立新的早期诊断方法。结果:姐妹染色单体互换频率产前诊断率为61.76%,B型超声为52.94%,宫高腹围为26.09%,姐妹染色单体互换频率阳性检出率为75%,孕20周前阳性检出率为76.19%,三种指标综合判断可使产前诊断率提高到82.19%。结论:多种指标判断可以提高产前诊断率,姐妹染色单体互换频率可以作为一项产前诊断胎儿宫内生长迟缓的新指标
Methods: Using sister chromatid exchange frequency, B-mode ultrasound, uterine height and abdominal circumference three indicators to determine prenatal diagnosis of fetal growth retardation. Objective: To improve the rate of prenatal diagnosis and establish a new early diagnosis. Results: The prenatal diagnosis rate of sister chromatid exchange was 61.76%, type B ultrasound was 52.94%, high uterine circumference was 26.09%, sister chromatid exchange rate was 75%, and pregnancy rate was 20 weeks Pre-positive detection rate of 76.19%, three indicators of comprehensive judgment can make the prenatal diagnosis rate increased to 82.19%. Conclusion: Multiple indicators can improve the rate of prenatal diagnosis, sister chromatid exchange frequency can be used as a prenatal diagnosis of fetal growth retardation of a new indicator