早在本世纪初，Ａｌｓｂｅｒｇ等在研究镉的药理作用时，发现镉对睾丸具有很强的坏死作用，但当时未引起足够的重视［１］。３０年代，日本“痛痛病”的发生被证明与镉接触有关。由此人们开始关注镉对人体的危害。５０年代，Ｐａｒｉｚｋｅ发现动物皮下注射镉盐后，数小时内睾 As early as the beginning of this century, Alsberg and others studied the pharmacological effects of cadmium and found that cadmium had a strong necrotic effect on testis, but at the time did not pay enough attention [1]. In the 1930s, the occurrence of “toothache” in Japan was shown to be related to cadmium exposure. As a result, people began to pay attention to the harm of cadmium to the human body. In the 1950s, Parizke found that within a few hours after injection of cadmium salts into animals, the testicles were found