患者女性,56岁,1992年2月行全子宫双附件切除术,病理诊断为“子宫内膜管状腺瘤”,术后接受免疫抑制剂治疗及两个疗程放疗。1995年2月又行左肺下叶肺癌肺叶切除术,病理诊断为“肺周围型中度或低分化鳞状细胞癌伴坏死形成”。患者乙肝标志物三项阳性,有典型家族史,母患乳腺癌,姐患胃癌,弟患肝癌。讨论:多原发癌的诊断标准:(1)每一个肿瘤必须是恶性的;(2)每个肿瘤有其特殊的病理形态;(3)必须明确排除为他瘤的转移。据时间隔分,两个或多个肿瘤发生在6个月以内为同时性癌,超过6个月为异时性癌。多原发癌的发生与患者的易感性、免疫 Female patients, 56 years old, February 1992, the whole hysterectomy double attachment, the pathological diagnosis of “endometrial tubular adenoma,” after receiving immunosuppressive agents and two courses of radiotherapy. February 1995 line of the lower lung lung lobectomy again, the pathological diagnosis of “moderate or poorly differentiated lung squamous cell carcinoma with necrosis.” Hepatitis B markers in patients with three positive, a typical family history, mother and child breast cancer, sister suffering from gastric cancer, brother suffering from liver cancer. Discussion: Multiple primary cancer diagnostic criteria: (1) each tumor must be malignant; (2) each tumor has its own special pathological form; (3) must be explicitly excluded for his tumor metastasis. According to the time interval, two or more tumors occurred within 6 months for simultaneous cancer, more than 6 months for heterogenous cancer. More primary cancer and the occurrence of patients with susceptibility to immune