糖尿病神经病变是常见的糖尿病并发症之一,其中有肢体疼痛、感觉异常等多种表现,其中以疼痛最痛苦、最显著[1],临床多见于血糖控制不佳的患者,常表现为远端肢体自发性疼痛、痛觉过敏、异常性疼痛(如烧灼感、蚁走感或针刺感)等,夜间明显[2],同时患者常合并抑郁、失眠[3],且治疗 Diabetic neuropathy is one of the common complications of diabetes, including limb pain, sensory abnormalities and many other manifestations, of which pain is the most painful, the most significant [1], clinical more common in patients with poor blood glucose control, often manifested as far End limbs, spontaneous pain, hyperalgesia, allodynia (such as burning sensation, ants walking feeling or acupuncture), etc., obvious at night [2], while patients often associated with depression and insomnia [3], and treatment