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目的观察扶正清疣汤内服外洗联合二氧化碳激光治疗尖锐湿疣的临床疗效。方法纳入我科收治的尖锐湿疣患者123例,根据治疗方法分为治疗组55例和对照组68例,对照组采用CO_2激光联合5-氨基酮戊酸光动力治疗,治疗组在CO_2激光治疗基础上配合扶正清疣汤内服外洗治疗,随访3个月,观察两组复发情况及不良反应。结果治疗组和对照组治愈率分别为89.09%和91.18%,两组间差异没有统计学意义(P>0.05);随访3个月期间内,对照组累计6例复发,总复发率为8.82%;治疗组累计6例复发,总复发率为10.91%,复发多在治疗后3~5周。治疗组第2周复发率显著高于对照组,但两组之间复发率差异没有统计学意义(P>0.05),4周以后两组复发率没有显著差异(P>0.05)。两组均未出现严重不良反应。结论扶正清疣汤内服外洗联合CO_2激光治疗CA可以提高临床疗效,降低复发率。
Objective To observe the clinical effect of Fuzheng Qingwuxu Decoction combined with external washing and carbon dioxide laser in the treatment of condyloma acuminatum. Methods 123 patients with condylomata acuminatum treated in our department were divided into treatment group (55 cases) and control group (68 cases). The control group was treated with CO2 laser combined with 5-aminolevulinic acid photodynamic therapy. The treatment group was treated with CO2 laser treatment Combined with Fuzheng Qing wart soup oral administration of external wash treatment, followed up for 3 months, observed the recurrence of the two groups and adverse reactions. Results The cure rates of the treatment group and the control group were 89.09% and 91.18%, respectively, with no significant difference between the two groups (P> 0.05). During the 3-month follow-up period, the control group had 6 cases relapsed with a total recurrence rate of 8.82% ; Treatment group, a total of 6 cases of recurrence, the total recurrence rate was 10.91%, recurrence and more in the treatment of 3 to 5 weeks. The recurrence rate in the second week of the treatment group was significantly higher than that in the control group, but there was no significant difference in the recurrence rate between the two groups (P> 0.05). There was no significant difference in recurrence rate between the two groups after 4 weeks (P> 0.05). No serious adverse reactions occurred in either group. Conclusion Fuzheng clear wart decoction combined with CO_2 laser treatment of external washing can improve clinical efficacy and reduce the recurrence rate.