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对16年来在Walter Reed陆军医疗中心因Ⅰ期宫颈癌行根治性子宫切除及盆腔和腹主动脉旁淋巴结清扫术的124例患者进行了调查研究,其中不包括术后放化疗及复发病例。所有同时行双侧附件切除术的患者,术后均给予激素替代治疗。调查内容包括确诊时的月经情况,术后出现的绝经期症状,是否合理应用激素,手术前后对比性快感有无变化,保留一侧或双侧卵巢的妇女需查血清促性腺激素水平。客观资料均经查阅门诊及住院病历证实。统计学分析采用非配对t检验及Yates校正x~2检验。其目的在于评价早期宫颈癌患者保留卵巢的利弊。
124 patients who underwent radical hysterectomy and pelvic and paraaortic lymphadenectomy for stage I cervical cancer at the Walter Reed Army Medical Center over 16 years were excluded from postoperative chemoradiation and relapse. All patients who underwent simultaneous bilateral resection were given hormone replacement therapy after operation. The survey included the menstrual status at the time of diagnosis, the postmenopausal symptoms, whether or not the hormone was used reasonably, whether there was any change in the contrast before and after surgery, and women with one or both ovaries to be examined for serum gonadotropin levels. Objective data were confirmed by outpatient and inpatient medical records. Statistical analysis using unpaired t test and Yates calibration x ~ 2 test. Its purpose is to evaluate the pros and cons of preserving ovaries in patients with early cervical cancer.