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为评估头皮放疗患者肿瘤发生的危险性,对照研究了历史人群和前瞻性的随访病例。受照射人群包括10834名儿童,其年龄、性别、种族均为配对资料,5392名为兄弟姐妹做对照。对于唾液腺照射计算剂量:每次为78CGy(范围63~286 CGy)。随访时间1950年至1991年底。失访率(研究组与对照组)为1.9%。结果表明,不论良性或恶性,大多数肿瘤位于腮腺。癌症发病率4.5倍(P<0.01),良性肿瘤增加2.6倍。肿瘤发
To assess the risk of developing tumors in patients with scalp radiotherapy, a control study of the historical population and prospective follow-up was conducted. Irradiated people include 10,834 children, their age, gender, race are paired information, 5,392 for siblings as a control. Dose calculated for salivary gland irradiation: 78CGy each (range 63 to 286 CGy). Follow-up time from 1950 to the end of 1991. The loss rate (study group and control group) was 1.9%. The results show that most tumors, whether benign or malignant, are located in the parotid gland. The incidence of cancer was 4.5 times (P <0.01), benign tumors increased by 2.6 times. Tumor hair