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目的 观察肝局灶性结节性增生 (FNH)的病理特点。方法 采用HE和免疫组化技术对 5例FNH进行病理学观察。结果 5例FNH临床均误诊为肝癌。术后随访 4例 ,4月～ 11年 ,健在。FNH病理学特征为孤立的、有纤维疤痕的结节性肿块。纤维疤痕中可见厚壁血管。CD34在肝血窦内皮细胞呈阳性。讨论 纤维疤痕是FNH的形态特征。应与肝细胞癌 ,纤维板层状肝癌及肝腺瘤鉴别。FNH的病因可能与局部血循障碍有关
Objective To observe the pathological features of focal liver nodular hyperplasia (FNH). Methods Five cases of FNH were studied by HE and immunohistochemistry. Results Five patients with FNH were misdiagnosed as liver cancer. Four patients were followed up for 4 months, and they were alive between April and 11 years. The pathological features of FNH are isolated, fibrous nodular nodular masses. Thick blood vessels can be seen in the fiber scars. CD34 was positive in hepatic sinusoidal endothelial cells. Discussion Fiber scars are the morphological features of FNH. Should be differentiated from hepatocellular carcinoma, fibrin lamellar liver cancer and hepatic adenoma. The cause of FNH may be related to local blood circulation disorder