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目的评估常州市武进区居民的总体碘营养状况,了解不同人群之间碘营养状况差异,探讨碘营养状况与甲状腺疾病之间的相关性。方法采集该市武进区14个乡镇社区292个家庭食盐样本,以及每位研究者的空腹尿液样本,采用砷铈催化分光光度计法测定尿碘浓度,直接滴定法测定盐碘含量,并采用电化学发光法检测这些研究者的血清甲状腺功能。结果武进地区成年人碘营养适量,但学龄儿童处于超足量范围,孕妇则碘营养不足;武进地区男性女性居民之间尿碘水平差异无统计学意义(P>0.05),但甲功异常居民尿碘水平(218.53±133.26μg/L)明显高于甲功正常者尿碘水平(188.18±110.91μg/L)(P<0.05)。结论常州武进地区不同人群之间碘营养存在个体差异,碘盐标准的制定需考虑不同地区环境的碘含量差异及不同人群对碘需求不同等因素个体化科学补碘。
Objective To evaluate the overall iodine nutrition status of residents in Wujin District, Changzhou City, and to understand the differences in iodine nutrition among different populations and to explore the correlation between iodine nutrition status and thyroid disease. Methods A total of 292 household salt samples from 14 townships in Wujin District of the city were collected, and the fasting urine samples of each researcher were collected. Urine iodine concentration was determined by arsenic and cerium catalytic spectrophotometer. Salt iodine content was determined by direct titration. Electrochemiluminescence was used to examine the serum thyroid function of these investigators. Results The amount of iodine nutrition in adults in Wujin district was moderate, but the number of school-age children exceeded the threshold and iodine deficiency in pregnant women. There was no significant difference in urine iodine level among male female inhabitants in Wujin area (P> 0.05) The urinary iodine level (218.53 ± 133.26μg / L) was significantly higher than that of normal thyroid function (188.18 ± 110.91μg / L) (P <0.05). Conclusion There are individual differences in iodine nutrition among different populations in Wujin area of Changzhou. The formulation of iodized salt standard should be based on individual differences in iodine content in different regions and individual needs of iodine in different populations.