论文部分内容阅读
目的分析广州市2004-2007年肾综合征出血热(HFRS)的流行特点和趋势,为制定防治策略提供依据。方法收集广州地区疫情资料,描述其流行病学特征。HFRS抗体与抗原检测采用免疫荧光分析。结果广州市2004-2007年共检出HFRS患者337例,年发病率0.59/10万～0.92/10万(平均0.73/10万),病死率0.89%。病例多为青壮年男性民工及商业服务者,主要分布于海珠和天河等地,发病高峰主要在春秋季。鼠间疫情监测显示鼠密度为10.3%,总带毒率为3.6%(160/4457),优势鼠为褐家鼠,带毒率为4.8%(132/2756)。结论广州HFRS疫情有上升趋势,应加大疫情监测力度,认真做好防鼠灭鼠及重点人群的疫苗接种工作。
Objective To analyze the epidemiological characteristics and trends of hemorrhagic fever with renal syndrome (HFRS) in Guangzhou from 2004 to 2007, and provide the basis for making prevention and treatment strategies. Methods The data of epidemic situation in Guangzhou were collected and their epidemiological characteristics were described. HFRS antibody and antigen detection using immunofluorescence analysis. Results A total of 337 HFRS patients were detected in Guangzhou from 2004 to 2007, with an annual incidence of 0.59 / 100,000 to 0.92 / 100,000 (average 0.73 / 100,000) and a case fatality rate of 0.89%. Cases are mostly young men and migrant workers and commercial service workers, mainly in Haizhu and Tianhe and other places, the peak incidence in the spring and autumn. The outbreak surveillance showed that the rat density was 10.3%, the total virulence rate was 3.6% (160/4457), and the predominant mouse was Rattus norvegicus with a virological rate of 4.8% (132/2756). Conclusion The epidemic situation of HFRS in Guangzhou is on an upward trend. It is necessary to intensify the surveillance of epidemic situation and conscientiously do a good job in anti-rodent control and vaccination of key populations.