论文部分内容阅读
目的目的比较肠内及肠外营养(Parenteral nutrition PN)支持治疗重症急性胰腺炎(Severe acute pancreatitis,SAP)的临床效果,了解肠内营养(Enteral nutrition EN)的可行性及其优势。方法回顾分析近2年中我院收治的52例SAP患者的临床资料,按是否接受EN分成EN组(30例)和常规治疗组(22例),分析患者的一般资料,观察比较两组患者营养支持后第7、14天的营养状况、突出生化指标。结果给予营养支持后,两组患者血、尿淀粉酶和血糖明显降低,血钙明显升高(P<0.05)。与PN组比较,EN组血清白蛋白显著升高,血白细胞明显降低(P<0.05);肝功能损害EN组均低于PN组。结论 EN支持是SAP重要治疗手段,在无绝对禁忌证的情况下,对SAP患者尽早给予EN是安全和有效的,较PN能够获得较好的营养状态。
Objective To compare the clinical effects of Parenteral nutrition (PN) supportive therapy in patients with severe acute pancreatitis (SAP) and to evaluate the feasibility and advantages of Enteral nutrition EN. Methods The clinical data of 52 patients with SAP admitted in our hospital in recent 2 years were retrospectively analyzed. According to whether EN was divided into EN group (n = 30) and routine treatment group (n = 22), the general data of patients were analyzed. Nutritional support 7 and 14 days after the nutritional status, highlighting biochemical indicators. Results After nutritional support, blood and urine amylase and blood glucose were significantly decreased and blood calcium was significantly increased in both groups (P <0.05). Compared with PN group, serum albumin in EN group was significantly increased and leukocyte count was significantly decreased (P <0.05). In EN group, EN group was lower than PN group. Conclusions EN support is an important treatment for SAP. It is safe and effective to treat EN patients as early as possible without any absolute contraindications, which is better than PN in obtaining nutritional status.