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目的:探讨苯磺酸氨氯地平治疗原发性高血压的临床疗效。方法:将我院2010年1月到2011年7月收治的80例原发性高血压患者随机分为对照组与观察组,每组40例。对照组给予尼群地平治疗,观察组给予苯磺酸氨氯地平治疗。观察两组患者血压控制情况、临床疗效以及不良反应发生情况。结果:两组治疗前后的血压比较差异无统计学意义(P>0.05);观察组的临床显效率和总有效率与对照组比较无显著性差异(P>0.05);观察组不良反应发生率明显低于对照组(P<0.05)。结论:苯磺酸氨氯地平治疗原发性高血压的临床疗效确切,不良反应小,值得在临床中推广应用。
Objective: To investigate the clinical efficacy of amlodipine besylate in the treatment of essential hypertension. Methods: Eighty patients with essential hypertension admitted to our hospital from January 2010 to July 2011 were randomly divided into control group and observation group, 40 cases in each group. The control group was treated with nitrendipine, and the observation group was treated with amlodipine besylate. The two groups of patients were observed blood pressure control, clinical efficacy and adverse reactions. Results: There was no significant difference in blood pressure between the two groups before and after treatment (P> 0.05). There was no significant difference between the two groups in the clinical effective rate and the total effective rate (P> 0.05). The incidence of adverse reactions in the observation group Significantly lower than the control group (P <0.05). Conclusion: The clinical efficacy of amlodipine besylate in the treatment of essential hypertension is definite and the adverse reactions are small. It is worth to be popularized in clinic.