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目的:分析尼莫地平与法舒地尔治疗蛛网膜下腔出血的临床疗效。方法:按照入院顺序将91例蛛网膜下腔出血患者进行逐一编号、分组,法舒地尔组(单号)46例给予静脉滴注盐酸法舒地尔治疗;尼莫地平组(双号)45例给予尼莫地平治疗,均治疗30天末观察临床疗效和大脑中动脉血流速度(VMCA)。结果:尼莫地平组总有效率91.11%明显优于法舒地尔组73.91%,P<0.05;尼莫地平组平均VMCA速度78.5±6.5cm/s明显优于法舒地尔组98.4±6.3cm/s,P<0.01。结论:尼莫地平治疗蛛网膜下腔出血疗效确切,在改善临床症状、体征和VMCA速度方面优于法舒地尔,值得临床继续研究和探讨。
Objective: To analyze the clinical efficacy of nimodipine and fasudil in the treatment of subarachnoid hemorrhage. Methods: Ninety-one patients with subarachnoid hemorrhage were assigned to one group according to the order of hospital admission, and 46 fasasil group (single) were given intravenous fasudil hydrochloride. The nimodipine group (double number) 45 cases were given nimodipine treatment, were treated for 30 days to observe the clinical efficacy and the middle cerebral artery blood flow velocity (VMCA). Results: The total effective rate of nimodipine group was 91.11%, which was significantly better than that of fasudil group (73.91%, P <0.05). The average VMCA speed of nimodipine group was 78.5 ± 6.5cm / s, which was significantly better than fasudil group 98.4 ± 6.3 cm / s, P <0.01. Conclusion: Nimodipine is effective in the treatment of subarachnoid hemorrhage and is superior to Fasudil in improving clinical symptoms, signs and VMCA speed. It is worth further study and discussion.