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目的:探讨氯吡格雷联合阿司匹林治疗急性心肌梗死的临床效果。方法:以2013年2月-2015年2月本院收治的86例急性心肌梗死患者为研究对象,按照住院先后顺序将其分为研究组(氯吡格雷+阿司匹林)与对照组(阿司匹林)。对比分析两组患者住院期间心脑血管事件发生情况及治疗前、治疗后后90d时左室射血分数变化情况。结果:治疗后,研究组住院期间心脑血管事件发生率(7.0%),明显低于对照组(25.6%),二者有显著性差异(P<0.05);治疗前,两组患者左室射血分数无显著性差异(P>0.05);治疗后90d时研究组左室射血分数明显优于对照组,二者有显著性差异(P<0.05)。结论:氯吡格雷联合阿司匹林治疗急性心肌梗死有着较好的临床效果,能改善患者左室功能,减少心脑血管事件的发生。
Objective: To investigate the clinical effect of clopidogrel combined with aspirin in the treatment of acute myocardial infarction. Methods: Totally 86 acute MI patients treated in our hospital from February 2013 to February 2015 were enrolled in the study group (clopidogrel + aspirin) and control group (aspirin) according to the order of hospitalization. The occurrence of cardiovascular events during hospitalization and the changes of left ventricular ejection fraction at 90 days after treatment were compared between the two groups. Results: After the treatment, the incidence of cardiovascular events during the hospitalization of the study group (7.0%) was significantly lower than that of the control group (25.6%) (P <0.05). Before treatment, the left ventricular There was no significant difference in ejection fraction between the two groups (P> 0.05). At 90 days after treatment, LV ejection fraction was significantly higher in the study group than in the control group (P <0.05). Conclusion: Clopidogrel combined with aspirin in the treatment of acute myocardial infarction has a good clinical effect, can improve left ventricular function in patients with cardiovascular and cerebrovascular events.