Expeditious solvent-free synthesis of 1,3-thiazolanes via multicomponent reactions

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A series of 1 3-thiazolane derivatives have been synthesized via multicomponent reactions of activated acetylenes,primary amines and isothiocyanates in the presence of a catalytic amount of Nmethylimidazole under solvent-free conditions. A series of 1 3-thiazolane derivatives have been synthesized via multicomponent reactions of activated acetylenes, primary amines and isothiocyanates in the presence of a catalytic amount of Nmethylimidazole under solvent-free conditions.
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