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[目的]评价间歇充气加压(IPC)治疗对重症监护室(ICU)慢性阻塞性肺病急性加重期(AECOPD)患者下肢深静脉血栓(DVT)的预防作用。[方法]采用临床随机对照试验的方法,将入住某医院重症监护室的AE-COPD患者随机分成治疗组和对照组,治疗组采用IPC治疗预防下肢DVT形成,对照组采用常规方法。观察两组下肢DVT的发生率,机械通气时间,ICU住院日,ICU的死亡率。[结果]治疗组下肢DVT的发生率明显低于对照组(P﹤0.05),两组机械通气时间,ICU住院日,ICU的死亡率差异无统计学意义(P﹥0.05)。[结论]IPC治疗对预防重症监护室AECOPD患者下肢DVT形成有效。
[Objective] To evaluate the preventive effect of intermittent inflation pressure (IPC) on lower extremity deep vein thrombosis (DVT) in intensive care unit (ICU) patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD). [Methods] The AE-COPD patients admitted to a hospital intensive care unit were randomly divided into treatment group and control group by clinical randomized controlled trial. The treatment group was treated with IPC to prevent lower limb DVT formation. The control group was treated with routine method. The incidence of DVT in lower extremities, duration of mechanical ventilation, length of stay in ICU, and mortality in ICU were observed. [Results] The incidence of DVT in the lower limbs of the treatment group was significantly lower than that of the control group (P <0.05). There was no significant difference in the duration of mechanical ventilation, ICU stay, and ICU mortality between the two groups (P> 0.05). [Conclusion] IPC treatment is effective in preventing lower extremity DVT formation in patients with AECOPD in intensive care unit.