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目的为瘢痕子宫中晚期妊娠引产探索一种安全、有效的引产方式。方法回顾性分析2010年1月至2014年12月于郑州大学人民医院产科引产的瘢痕子宫孕妇118例,孕周为15~33周,将其分为2组,A组为米非司酮联合依沙吖啶引产,共61例,B组为米非司酮联合水囊引产,共57例;比较分析这2种引产方式的产程、引产成功率、产后出血量、胎盘胎膜残留率及严重并发症发生率。结果两组孕妇产后出血量、胎盘胎膜残留率比较差异无统计学意义(P>0.05),B组引产时间短于A组,差异有统计学意义(P<0.05),B组引产成功率高于A组,差异有统计学意义(P<0.05),两组均未出现严重并发症。结论米非司酮联合依沙吖啶或水囊在瘢痕子宫中晚期妊娠引产中均安全、有效,但是米非司酮联合水囊引产成功率更高,引产时间更短,适用范围更广;2种引产方式引产过程中均需严密监测。
Objective To explore a safe and effective induction of labor for late pregnant pregnancy induced by uterine scar. Methods A retrospective analysis of 118 cases of scarring uterus induced by obstetrical gynecology in Zhengzhou University People’s Hospital from January 2010 to December 2014 was performed. The gestational age ranged from 15 to 33 weeks. The patients were divided into two groups. Group A was mifepristone Among them, 61 cases were induced by ethacridine, 57 cases were induced by mifepristone combined with water balloon in group B. The labor course, the success rate of induction of labor, the amount of postpartum hemorrhage, the residual rate of placental membranes, Serious complication rate. Results There was no significant difference in postpartum hemorrhage volume and residual rate of placental membranes between the two groups (P> 0.05), and the induction time in group B was shorter than that in group A (P <0.05). The success rate of induction of labor in group B Higher than that of A group, the difference was statistically significant (P <0.05), no serious complications occurred in both groups. Conclusions Both mifepristone combined with ethacridine and water sac are safe and effective in inducing abortion in middle and late stage of uterine scar pregnancy. However, the successful rate of induction of labor with mifepristone combined with water sac is higher, and the time for induction of labor is shorter and the scope of application is wider. Two kinds of induced labor induced abortion process must be closely monitored.