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防龋疫苗的研究经历了三个阶段,目前国外仍将变链菌细胞表面蛋白抗原Ⅰ/Ⅱ和葡糖基转移酶蛋白抗原基因工程重组疫苗作为研究的重点。本文对基因重组防龋疫苗的研究近况进行了综述。
The research of caries-preventing vaccine has gone through three stages. At present, the foreign recombinant DNA vaccine of Streptococcus mutans surface antigen Ⅰ / Ⅱ and glucosyltransferase antigen are still the focus of research. This review summarizes the current situation of genetically modified anti-caries vaccine.