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目的观察中西药联合治疗内分泌失调性骨质疏松症的临床效果。方法将2015年3月-2017年3月医院收治的内分泌失调性骨质疏松症患者64例随机分为2组,每组32例,对照组采用常规西药治疗,包括鲑鱼降钙素喷剂、碳酸钙维生素D、甲睾酮、塞来昔布胶囊、阿仑膦酸钠等;观察组在对照组治疗的基础上给予中药治疗,比较2组患者的临床效果及骨密度(BMD)指标。结果观察组总有效率为87.5%高于对照组的62.5%,差异有统计学意义(P<0.05)。观察组股骨颈BMD、大转子BMD、Wards三角区BMD均高于对照组,差异均有统计学意义(P<0.05)。结论中西药联合治疗内分泌失调性骨质疏松症的治疗效果显著,可明显改善患者的临床症状,值得临床推广。
Objective To observe the clinical efficacy of the combination of Chinese and Western medicine in the treatment of endocrine disorders of osteoporosis. Methods 64 patients with endocrine disorders and osteoporosis who were admitted to our hospital from March 2015 to March 2017 were randomly divided into two groups (n = 32 in each group). The control group was treated with conventional western medicine including salmon calcitonin spray, Calcium carbonate, vitamin D, methyltestosterone, celecoxib capsules, alendronate and so on. The observation group was treated with traditional Chinese medicine on the basis of the control group. The clinical effect and the bone mineral density (BMD) index of the two groups were compared. Results The total effective rate in observation group was 87.5% higher than that in control group (62.5%), the difference was statistically significant (P <0.05). The BMD of femoral neck BMD, greater trochanter BMD and Wards triangle in the observation group were higher than those in the control group, with statistical significance (P <0.05). Conclusion Chinese and Western medicine combined treatment of endocrine disorders osteoporosis treatment effect is significant, can significantly improve the clinical symptoms of patients, it is worth clinical promotion.