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本文研究７．５％ＮａＣｌ溶液在常用量（４ｍｌ／ｋｇ）时对血液稀释和红细胞本身的影响。选择手术病人１５例，平均年龄３６．９±１０．２岁。手术前采静脉血作为对照，然后经静脉输７．５％的ＮａＣｌ溶液２００～２５０ｍｌ在１０～２０ｍｉｎ内输完（按４ｍｌ／ｋｇ计算）。立即采取第２次血标本，以后在３０ｍｉｎ、６０ｍｉｎ和１２０ｍｉｎ分别采取第３、４、５次血标本，注入含肝素的抗凝试管中，用ＭｉｃｒｏｃｅｌＣｏｕｎｔｅｒ（Ｈ－８００型）测试计算红细胞参数。结果提示，静注７．５％ＮａＣｌ后有轻度血液稀释、红细胞平均体积有缩小现象，血红蛋白浓度无变化，不影响红细胞携氧功能。结论：任意加大ＨＳ用量，特别在短时间内输入，对红细胞将会产生损害。
This article studies the effect of a 7.5% NaCl solution on hemodilution and erythrocyte itself at the usual dose (4 ml / kg). Fifteen patients were selected for surgery, with an average age of 36.9 ± 10.2 years. Venous blood collected before surgery as a control, and then intravenous infusion of 7.5% NaCl solution 200 ~ 250ml lost in 10 ~ 20min (press 4ml / kg basis). The second blood sample was taken immediately. The third, fourth and fifth blood samples were taken at 30min, 60min and 120min respectively and then injected into anticoagulant tubes containing heparin. The parameters of erythrocytes were calculated by MicrocelCounter (H-800 type). The results suggest that, after 7.5% NaCl intravenous mild hemodilution, the average volume of red blood cells shrink, hemoglobin concentration did not change, does not affect the red blood cell oxygen carrying function. Conclusion: Any increase in the amount of HS, especially in a short period of input, the red blood cells will have damage.