用ＡＢＣ和ＩＧＳＳ法对１０例膀胱组织，２例腺性膀胱炎组织，１例膀胱异位嗜铬细胞瘤组织的癌胚抗原进行免疫组化变化的研究，结果表明１０例癌组织的染色均为阳性，阳性率为１００％。２例腺性膀胱炎和１例异位嗜铬细胞瘤组织为阴性，ＣＥＡ在阳性染色的膀胱癌组织中的定位主要为胞膜、胞浆混合型。阳性细胞在膀胱癌组织中的分布主要在上皮的表层，检查膀胱组织ＣＥＡ可以作为膀胱癌诊断和鉴别诊断的一种手段。 ABC and IGSS method of 10 cases of bladder tissue, 2 cases of cystitis glandularis, 1 case of bladder ectopic pheochromocytoma carcinoembryonic antigen immunohistochemical study showed that 10 cases of cancer tissue staining were Positive, the positive rate of 100%. Two cases of cystitis glandularis and one case of ectopic pheochromocytoma were negative. The localization of CEA in the positive stained bladder cancer tissues was mainly cytoplasm and cytoplasm mixed type. Positive cells in bladder cancer tissue distribution mainly in the epithelial surface, check the bladder tissue CEA can be used as a diagnosis and differential diagnosis of bladder cancer as a means.