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摘要目的比较单倍与半倍剂量钆贝葡胺对疾病活动度评分>3.2的早期类风湿性关节炎手指关节滑膜炎或腱鞘炎的诊断效能。材料与方法本研究获得伦理审查委员会的批准和同意。早期类风湿性关节炎57例行3.0 T MR成像。分别注射半倍剂量(0.05 mmol/kg体质量)和单倍剂量(0.1 mmol/kg体质量)对比剂,评价T1WI脂肪抑制序列上炎性滑膜组织强化程度。采用配对t检验和Pearson相关检验比较2次影像滑膜信号强度的差异性和相关性。2名阅片者分别对半倍剂量和单倍剂量对比剂获得的影像行影像质量评分、类风湿关节炎MRI评分(依RAMRIS系统)和腱鞘滑
Abstract Objective To compare the diagnostic efficacy of single and half-fold doses of gadopentethbendramine in the treatment of finger joint synovitis or tenosynovitis of early-stage rheumatoid arthritis with a disease activity score> 3.2. Materials and Methods The study was approved and agreed by Ethics Review Board. 57 cases of early rheumatoid arthritis 3.0 T MR imaging. Inflammatory synovial tissue enhancement on the T1WI fat suppression sequence was evaluated by injecting a half-dose (0.05 mmol / kg body weight) and a single dose (0.1 mmol / kg body weight) contrast agent respectively. The paired t-test and Pearson correlation test were used to compare the differences and correlations of signal intensities in the secondary images. Two reviewers evaluated the image quality of the images obtained from the half-dose and the single-dose contrast media, the MRI score of the rheumatoid arthritis (according to the RAMRIS system), and the tendon sheath slip